Guang-Di Chen Selected Research

Hyperacusis (Phonophobia)

10/2021	Review: Neural Mechanisms of Tinnitus and Hyperacusis in Acute Drug-Induced Ototoxicity.
1/2021	Functional Neuroanatomy of Salicylate- and Noise-Induced Tinnitus and Hyperacusis.
1/2020	Functional magnetic resonance imaging of enhanced central auditory gain and electrophysiological correlates in a behavioral model of hyperacusis.
12/2019	Noise-Induced loudness recruitment and hyperacusis: Insufficient central gain in auditory cortex and amygdala.
1/2019	Intermittent Low-level Noise Causes Negative Neural Gain in the Inferior Colliculus.
1/2017	Plastic changes along auditory pathway during salicylate-induced ototoxicity: Hyperactivity and CF shifts.
1/2017	Tinnitus and hyperacusis: Contributions of paraflocculus, reticular formation and stress.
5/2015	Tinnitus and hyperacusis involve hyperactivity and enhanced connectivity in auditory-limbic-arousal-cerebellar network.
11/2012	Amygdala hyperactivity and tonotopic shift after salicylate exposure.

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Guang-Di Chen Research Topics

Disease

15	Hearing Loss (Hearing Impairment) 01/2022 - 07/2007
9	Hyperacusis (Phonophobia) 10/2021 - 11/2012
9	Tinnitus 10/2021 - 06/2010
5	Ototoxicity 01/2022 - 07/2007
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 10/2019
2	Deafness (Deaf Mutism) 01/2022 - 07/2007
2	Sensorineural Hearing Loss 01/2017 - 09/2015
2	Neoplasms (Cancer) 01/2016 - 01/2014
2	Noise-Induced Hearing Loss (Acoustic Trauma) 03/2002 - 01/2002
1	Unilateral Hearing Loss 07/2022
1	Seizures (Absence Seizure) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Neuroinflammatory Diseases 01/2022
1	Hearing Disorders (Hearing Disorder) 01/2017
1	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/2014
1	Auditory Perceptual Disorders (Auditory Processing Disorder) 01/2014
1	Wounds and Injuries (Trauma) 08/2009
1	Retinal Degeneration 03/2009
1	Substance-Related Disorders (Drug Abuse) 08/2005
1	Hypoxia (Hypoxemia) 02/2005

Drug/Important Bio-Agent (IBA)

11	SalicylatesIBA 10/2021 - 06/2010
5	Pharmaceutical PreparationsIBA 01/2022 - 05/2015
4	Sodium Salicylate (Salicylate, Sodium)IBA 01/2021 - 01/2013
3	PlasticsIBA 07/2022 - 01/2014
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2021 - 01/2017
3	Styrene (Styrol)IBA 08/2009 - 07/2007
2	CyclodextrinsIBA 01/2022 - 01/2021
2	Hormones (Hormone)IBA 01/2022 - 01/2017
2	CholesterolIBA 01/2022 - 01/2021
2	CorticosteroneIBA 01/2022 - 01/2017
2	Biological ProductsIBA 10/2021 - 08/2012
2	Hydrogen Cyanide (Zyklon B)IBA 03/2002 - 01/2002
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2022
1	AntioxidantsIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Minocycline (Cyclops)FDA LinkGeneric 01/2022
1	Mitochondrial DNA (mtDNA)IBA 10/2019
1	Carboplatin (JM8)FDA LinkGeneric 01/2016
1	TransferasesIBA 01/2016
1	manganese chloride (manganese chloride, tetrahydrate)FDA Link 01/2016
1	Cysteine (L-Cysteine)FDA Link 01/2016
1	ezogabine (retigabine)IBA 09/2015
1	BMS204352IBA 09/2015
1	Potassium Channels (Potassium Channel)IBA 09/2015
1	rat MIRN27 microRNAIBA 01/2014
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2014
1	ORALIT (ORS)IBA 01/2014
1	MicroRNAs (MicroRNA)IBA 01/2014
1	Connexin 26IBA 01/2013
1	Therapeutic UsesIBA 03/2009
1	sulforaphaneIBA 03/2009
1	Acetylcarnitine (Alcar)IBA 07/2008
1	Biomarkers (Surrogate Marker)IBA 07/2007
1	Cocaine (Cocaine HCl)IBA 08/2005
1	Proteins (Proteins, Gene)FDA Link 02/2005
1	Actins (F Actin)IBA 02/2005
1	Carbon MonoxideIBA 01/2002

Therapy/Procedure

3	Therapeutics 01/2022 - 01/2019